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Figure 7. Schematic diagram illustrates the process whereby IL-17 treatment promotes IL-18 production in OASFs [osteoarthritis synovial fibroblasts].
Aging News

IL-17 Promotes IL-18 Production in Osteoarthritis Synovial Fibroblasts Via…

February 13, 2024February 13, 2024

PRESS RELEASE: A new research paper was published in Aging’s Volume 16, Issue 2, entitled, “IL-17 promotes IL-18 production via the MEK/ERK/miR-4492 axis in osteoarthritis synovial fibroblasts.”

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Figure 1. Experimental design for the results shown in Figures 3 and 4.
Aging News

Sirtuin 6 Activation Rescues the Age-Related Decline in DNA Damage Repair in Chondrocytes

December 19, 2023December 19, 2023

PRESS RELEASE: A new research paper was published in Aging’s Volume 15, Issue 23, entitled, “Sirtuin 6 activation rescues the age-related decline in DNA damage repair in primary human chondrocytes.”

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Figure 1. Experimental design. To investigate senescence in osteoarthritic chondrocytes, primary human articular chondrocytes (HACs) were stimulated with etoposide for 24 h (blue) or with IL-1β for 8 days (red) with treatment renewal at days 3 and 6. Senescence features were assessed at days 1 and 8 in both conditions by qPCR, WB, and immunofluorescence.
Aging News

DNA Damage-induced Senescence Model in Osteoarthritic Chondrocytes

September 20, 2023September 20, 2023

A new research paper was published in Aging’s Volume 15, Issue 17, entitled, “Development of a DNA damage-induced senescence model in osteoarthritic chondrocytes.”

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