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Aging (Aging-US) Authors

Accelerated Aging in Young Sickle Cell Patients Linked to Elevated T-cell p16INK4a
Aging News

Accelerated Aging in Young Sickle Cell Patients Linked to Elevated T-cell p16INK4a

December 11, 2024December 11, 2024

A new research paper was published in Aging (listed by MEDLINE/PubMed as “Aging (Albany NY)” and “Aging-US” by Web of Science) Volume 16, Issue 21 on November 14, 2024, entitled, “Adolescents and young adults with sickle cell disease exhibit accelerated aging with elevated T-cell p16INK4a expression.”

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Figure 8. PR55α level is much lower in human normal tissue specimens of older individuals compared to younger individuals and inversely correlates with p16 levels. Human normal tissue specimens derived from various organs/sites were analyzed for differences in PR55α and p16 expression by IHC.
Aging News

PR55α-controlled PP2A Inhibits p16 Expression and Blocks Cellular Senescence Induction

March 19, 2024

PRESS RELEASE: On March 4, 2024, a new research paper was published in Aging’s Volume 16, Issue 5, entitled, “PR55α-controlled protein phosphatase 2A inhibits p16 expression and blocks cellular senescence induction by γ-irradiation.”

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