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Aging-US.net features press releases on the latest aging research, plus interviews and from the distinguished network of authors who continue to publish their research with Aging-US.

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Aging Journal

Figure 4. Mechanisms of cell death induced by CUDC-907 in senescent cells.
Aging News

Characterization of the HDAC/PI3K Inhibitor CUDC-907 as a Novel Senolytic

April 25, 2023April 26, 2023

PRESS RELEASE: A new research paper was published in Aging’s Volume 15, Issue 7, entitled, “Characterization of the HDAC/PI3K inhibitor CUDC-907 as a novel senolytic.”

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Figure 5. Epithelial and endothelial cell populations mediate p21-dependent inflammatory responses following chronic LPS inhalation.
Aging News

p21 Facilitates Chronic Lung Inflammation via Epithelial and Endothelial Cells

April 17, 2023April 18, 2023

PRESS RELEASE: A new research paper was published on the cover of Aging’s Volume 15, Issue 7, entitled, “p21 facilitates chronic lung inflammation via epithelial and endothelial cells.”

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Figure 7. Summary schematic of MET+LEU effects during SD in muscle cells.
Aging News

Metformin & Leucine Prevent Cellular Senescence & Proteostasis Disruption

March 31, 2023March 31, 2023

PRESS RELEASE: A new research paper was published on the cover of Aging’s Volume 15, Issue 6, entitled, “Cellular senescence and disrupted proteostasis induced by myotube atrophy are prevented with low-dose metformin and leucine cocktail.”

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Figure 6. Senescence / Senescent EXO exchange promotes activated MSC phenotype.
Aging News

Aging | Senescence-Associated Exosomes Transfer Fibrosis to Neighboring Cells

March 17, 2023March 17, 2023

PRESS RELEASE: A new research paper was published in Aging’s Volume 15, Issue 5, entitled, “Senescence-associated exosomes transfer miRNA-induced fibrosis to neighboring cells.”

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Figure 1. Geroconversion as a form of growth.
Aging News

Aging | Cellular Senescence: When Growth Stimulation Meets Cell Cycle Arrest

March 2, 2023March 2, 2023

PRESS RELEASE: Aging published a new review paper in Volume 15, Issue 4, entitled, “Cellular senescence: when growth stimulation meets cell cycle arrest.”

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Figure 6. p16Ink4a-expressing cells do not proliferate or secrete SASP compared to other senescent cells.
Aging News

Aging | Clearance of p16Ink4a+ Cells: Limited Effects on B-Cell Mass and Proliferation in Mice

January 31, 2023January 31, 2023

PRESS RELEASE: A new research paper was published on the cover of Aging’s Volume 15, Issue 2, entitled, “Clearance of p16Ink4a-positive cells in a mouse transgenic model does not change β-cell mass and has limited effects on their proliferative capacity.”

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Aging
Aging News

Aging | Single Nuclei Profiling Identifies Cell Specific Markers of Skeletal Muscle Aging, Frailty, and Senescence

December 15, 2022December 16, 2022

PRESS RELEASE: A new research paper was published on the cover of Aging’s Volume 14, Issue 23, entitled, “Single nuclei profiling identifies cell specific markers of skeletal muscle aging, frailty, and senescence.”

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Aging
Aging Latest Issue News

Aging | Glutaminase Inhibitors Rejuvenate Human Skin via Clearance of Senescent Cells: A Study Using a Mouse/Human Chimeric Model

December 1, 2022December 1, 2022

PRESS RELEASE: A new research paper was published on the cover of Aging’s Volume 14, Issue 22, entitled, “Glutaminase inhibitors rejuvenate human skin via clearance of senescent cells: a study using a mouse/human chimeric model.”

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Aging
Aging News

Aging | Rapamycin Treatment Early in Life Reprograms Aging: Hyperfunction Theory and Clinical Practice

November 3, 2022November 3, 2022

PRESS RELEASE: A new research perspective was published on October 24, 2022, in Aging’s Volume 14, Issue 20, entitled, “Rapamycin treatment early in life reprograms aging: hyperfunction theory and clinical practice.”

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Aging
Aging News

Aging | Downregulation of Senescence-Associated Secretory Phenotype by Knockdown of Secreted Frizzled-Related Protein 4 Contributes to Prevention of Skin Aging

October 31, 2022October 31, 2022

PRESS RELEASE: A new research paper was published on the cover of Aging’s Volume 14, Issue 20, entitled, “Downregulation of senescence-associated secretory phenotype by knockdown of secreted frizzled-related protein 4 contributes to the prevention of skin aging.”

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