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Aging (Aging-US) Authors

Aging Volume 17, issue 3
Aging News

Senolytics Target Alzheimer’s-Linked Brain Enzymes Without Harming Healthy Ones

April 1, 2025April 1, 2025

A new research paper was published in Aging (Aging-US) on March 29, 2025, as the cover of Volume 17, Issue 3, titled “Differential senolytic inhibition of normal versus Aβ-associated cholinesterases: implications in aging and Alzheimer’s disease.”

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Senolytic ABT-263 Reduces Radiation-Induced Gastrointestinal Cancer
Aging News

Senolytic ABT-263 Reduces Radiation-Induced Gastrointestinal Cancer

February 18, 2025February 18, 2025

BUFFALO, NY—February 18, 2025 — A new research paper was published by Aging (Aging-US) on January 8, 2025, in Volume 17, Issue 1, titled “Senolytic agent ABT-263 mitigates low- and high-LET radiation-induced gastrointestinal cancer development in Apc1638N/+ mice.”

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ABT-263 Treatment Rejuvenates Aged Skin and Enhances Wound Healing
Aging News

ABT-263 Treatment Rejuvenates Aged Skin and Enhances Wound Healing

February 4, 2025February 4, 2025

A new research paper was published by Aging (Aging-US) on December 3, 2024, in Volume 17, Issue 1, titled “Topical ABT-263 treatment reduces aged skin senescence and improves subsequent wound healing.”

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Senolytics Dasatinib and Quercetin for Prevention of Pelvic Organ Prolapse in Mice
Aging News

Senolytics Dasatinib and Quercetin for Prevention of Pelvic Organ Prolapse in Mice

October 22, 2024October 22, 2024

PRESS RELEASE – A new research paper was published in Aging (listed by MEDLINE/PubMed as “Aging (Albany NY)” and “Aging-US” by Web of Science), Volume 16, Issue 19 on September 26, 2024, entitled, “Use of the senolytics dasatinib and quercetin for prevention of pelvic organ prolapse in a mouse animal model.”

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Modulating in vitro lung fibroblast activation via senolysis of senescent human alveolar epithelial cells
Aging News

Modulating in Vitro Lung Fibroblast Activation via Senolysis of Senescent Human Alveolar Epithelial Cells

July 17, 2024July 17, 2024

PRESS RELEASE: A new research paper was published in Aging’s Volume 16, Issue 13, entitled, “Modulating in vitro lung fibroblast activation via senolysis of senescent human alveolar epithelial cells.”

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Figure 5. Correlation between epigenetic clocks and immune cell types.
Aging News

A Longitudinal Study on Dasatinib, Quercetin, and Fisetin Senolytic Interventions

March 6, 2024

PRESS RELEASE: A new research paper was published in Aging’s Volume 16, Issue 4, entitled, “Exploring the effects of Dasatinib, Quercetin, and Fisetin on DNA methylation clocks: a longitudinal study on senolytic interventions.”

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Figure 1. Identification of CaV blockers as a potential new class of senolytics.
Aging News

Benidipine Calcium Channel Blocker Improves Cigarette Smoke-Induced Lung Emphysema

December 20, 2023December 21, 2023

PRESS RELEASE: A new research paper was published in Aging’s Volume 15, Issue 23, entitled, “Benidipine calcium channel blocker promotes the death of cigarette smoke-induced senescent cells and improves lung emphysema.”

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Figure 4. The secretome of senescent human lung fibroblasts as mediator of murine lung fibrosis.
Aging News

Human Senescent Fibroblasts Cause Lung Fibrosis in Mice

July 31, 2023July 31, 2023

PRESS RELEASE: A new research paper was published on the cover of Aging’s Volume 15, Issue 14, entitled, “Human senescent fibroblasts trigger progressive lung fibrosis in mice.”

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Figure 2. Cholangiocytes and perinodular hepatocytes display cellular senescence in BA livers.
Aging News

Senescence and Senotherapies in Biliary Atresia and Biliary Cirrhosis

June 28, 2023June 28, 2023

PRESS RELEASE: A new research paper was published in Aging’s Volume 15, Issue 11, entitled, “Senescence and senotherapies in biliary atresia and biliary cirrhosis.”

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Figure 4. Mechanisms of cell death induced by CUDC-907 in senescent cells.
Aging News

Characterization of the HDAC/PI3K Inhibitor CUDC-907 as a Novel Senolytic

April 25, 2023April 26, 2023

PRESS RELEASE: A new research paper was published in Aging’s Volume 15, Issue 7, entitled, “Characterization of the HDAC/PI3K inhibitor CUDC-907 as a novel senolytic.”

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