PRESS RELEASE: A new research paper was published in Aging’s Volume 15, Issue 3, entitled, “Metformin use history and genome-wide DNA methylation profile: potential molecular mechanism for aging and longevity.”
Aging (Aging-US) Authors
PRESS RELEASE: A new research paper was published in Aging’s Volume 15, Issue 3, entitled, “Epigenetic age and lung cancer risk in the CLUE II prospective cohort study.”
In Alzheimer’s disease (AD), platelets become dysfunctional and might contribute to amyloid beta deposition. Here, the researchers depleted platelets in one-year-old APP Swedish PS1 dE9 (APP-PS1) transgenic mice for five days, using intraperitoneal injections of an anti-CD42b antibody, and assessed changes in cerebral amyloidosis, plaque-associated neuritic dystrophy and gliosis…
PRESS RELEASE: A new research paper was published on the cover of Aging’s Volume 15, Issue 3, entitled, “Immune-mediated platelet depletion augments Alzheimer’s disease neuropathological hallmarks in APP-PS1 mice.”
PRESS RELEASE: A new research paper was published in Aging’s Volume 15, Issue 2, entitled, “Body weight influences musculoskeletal adaptation to long-term voluntary wheel running during aging in female mice.”
PRESS RELEASE: Dr. Blagosklonny published a new research perspective in Aging’s Volume 15, Issue 2, entitled, “Are menopause, aging and prostate cancer diseases?”
Type 2 diabetes is partly characterized by decreased β-cell mass and function which have been linked to cellular senescence. Despite a low basal proliferative rate of adult β-cells, they can respond to growth stimuli, but this proliferative capacity decreases with age and correlates with increased expression of senescence effector, p16Ink4a.