Aging (Aging-US) Authors
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PRESS RELEASE: Mikhail Blagosklonny, M.D., Ph.D., published a new research perspective about upcoming research at Altos Labs.
![Volume 14, Issue 8](https://aging-us.net/wp-content/uploads/2022/04/AgingV14N8-600x600.png)
TP53 is a master regulator of many signaling and apoptotic pathways involved in: aging, cell cycle progression, gene regulation, growth, apoptosis, cellular senescence, DNA repair, drug resistance, malignant transformation, metastasis, and metabolism. Most pancreatic cancers are classified as pancreatic ductal adenocarcinomas (PDAC)…
![Volume 14, Issue 7](https://aging-us.net/wp-content/uploads/2022/04/Aging_15Apr22_300dpi_600pxX775px-1-600x600.png)
Insulin-like growth factor (IGF)-binding proteins (IGFBPs) are secretory proteins that regulate IGF signaling. In this study, the researchers investigated the role of IGFBP5 in replicative senescence in embryonic mouse fibroblasts (MEFs).
![Volume 14, Issue 6](https://aging-us.net/wp-content/uploads/2022/03/Aging_31Mar22_300dpi_600pxX775px-1-600x600.png)
In this study, the researchers used a variety of target identification and prioritization techniques offered by the AI-powered PandaOmics platform, to propose a list of promising novel aging-associated targets that may be used for drug discovery.