In this work, the researchers investigated the effect of insulin-like growth factor 1 (IGF1) gene therapy on hypothalamic kisspeptin/GnRH neurons and on microglial cells, that mediate the inflammatory process related with the aging process…
Aging (Aging-US) Authors

PRESS RELEASE: A new research paper was published in Aging’s Volume 14, Issue 20, entitled, “Age-associated changes in microglia activation and Sirtuin-1- chromatin binding patterns.”

PRESS RELEASE: A new research perspective was published in Aging’s Volume 14, Issue 20, entitled, “Lamin A to Z in normal aging.”

The open-access journal Aging recently launched a new webpage showcasing the full Aging Scientific Integrity Process.

PRESS RELEASE: A new research perspective was published on October 24, 2022, in Aging’s Volume 14, Issue 20, entitled, “Rapamycin treatment early in life reprograms aging: hyperfunction theory and clinical practice.”

Dr. Ya-Jen Chiu discusses a research paper she co-authored that was published by Aging (Aging-US) in Volume 14, Issue 18, entitled, “Novel TRKB agonists activate TRKB and downstream ERK and AKT signaling to protect Aβ-GFP SH-SY5Y cells against Aβ toxicity.”

There is growing evidence that the appearance and texture of the skin that is altered during the aging process are considerably enhanced by the accumulation of senescent dermal fibroblasts. These senescent cells magnify aging via an inflammatory, histolytic, and senescence-associated secretory phenotype (SASP)…