Dr. Ya-Jen Chiu discusses a research paper she co-authored that was published by Aging (Aging-US) in Volume 14, Issue 18, entitled, “Novel TRKB agonists activate TRKB and downstream ERK and AKT signaling to protect Aβ-GFP SH-SY5Y cells against Aβ toxicity.”
Aging (Aging-US) Authors

There is growing evidence that the appearance and texture of the skin that is altered during the aging process are considerably enhanced by the accumulation of senescent dermal fibroblasts. These senescent cells magnify aging via an inflammatory, histolytic, and senescence-associated secretory phenotype (SASP)…

PRESS RELEASE: A new research paper was published on the cover of Aging’s Volume 14, Issue 20, entitled, “Downregulation of senescence-associated secretory phenotype by knockdown of secreted frizzled-related protein 4 contributes to the prevention of skin aging.”

Dr. Takushi Namba discusses a research paper he co-authored that was published by Aging (Aging-US), entitled, “Lotus germ extract rejuvenates aging fibroblasts via restoration of disrupted proteostasis by the induction of autophagy.”

PRESS RELEASE: A new review paper was published in Aging’s Volume 14, Issue 19, entitled, “RNA modifications in aging-associated cardiovascular diseases.”

Fedor Galkin, Scientific Director at Deep Longevity, Inc., discusses a research paper he co-authored that was published by Aging (Aging-US) in Volume 14, Issue 18, entitled, “Psychological factors substantially contribute to biological aging: evidence from the aging rate in Chinese older adults.”

PRESS RELEASE: A new research paper was published on the cover of Aging’s Volume 14, Issue 19, entitled, “Centenarians consistently present a younger epigenetic age than their chronological age with four epigenetic clocks based on a small number of CpG sites.”

In the present study, researchers estimated the DNA methylation-based age (DNAmage) using four epigenetic clocks based on a small number of CpGs in French centenarians and semi-supercentenarians (CSSC, n=214) as well as nonagenarians’ and centenarians’ offspring (NCO, n=143) compared to individuals from the French general population (CG, n=149)…