PRESS RELEASE: A new editorial paper was published in Aging (Aging-US) Volume 14, Issue 11, entitled, “WRNing for the right DNA repair pathway choice.”
Aging (Aging-US) Authors
PRESS RELEASE: In Aging’s latest cover paper, researchers conducted a new study to elucidate the potential role of HDAC4 in the regulation of cellular senescence and skin aging.
Histone deacetylases (HDACs) remove acetyl groups from lysine chains on histones and other proteins and play a crucial role in epigenetic regulation and aging. Previously, we demonstrated that HDAC4 is consistently downregulated in aged and ultraviolet (UV)-irradiated human skin in vivo. Cellular senescence is a permanent cell cycle arrest induced by various stressors…
Dennis Mangan and Dr. Mikhail Blagosklonny discuss how Dr. Blagosklonny’s cancer research led him to the study of aging, whether rapamycin is the most important anti-aging intervention currently available, his skepticism about metformin as an anti-aging drug, and more.
Dennis Mangan from MTOR LLC in Bakersfield, California details his theory article published by Aging (Aging-US), entitled, “Iron: an underrated factor in aging.”
PRESS RELEASE: In Aging’s latest cover paper, researchers discovered that protein levels of Humanin G are significantly lower in patients with age-related macular degeneration.
Inflammation plays a crucial role in the etiology and pathogenesis of AMD (Age-related Macular Degeneration). Humanin G (HNG) is a Mitochondrial Derived Peptide (MDP) that is cytoprotective in AMD and can protect against mitochondrial and cellular stress induced by damaged AMD mitochondria…