Aging (Aging-US) Authors
Drs. Drs. Carly Bobak, Cristian Coarfa, and Andrew DiNardo detail their research paper published by Aging (Aging-US), entitled, “Increased DNA methylation, cellular senescence and premature epigenetic aging in guinea pigs and humans with tuberculosis.”
Drs. Drs. Carly Bobak, Cristian Coarfa, and Andrew DiNardo detail their research paper published by Aging (Aging-US), entitled, “Increased DNA methylation, cellular senescence and premature epigenetic aging in guinea pigs and humans with tuberculosis.”
A new research paper was published in Aging Volume 14, Issue 16, entitled, “Systemic lipolysis promotes physiological fitness in Drosophila melanogaster.”
PRESS RELEASE: A new research paper was published in Aging’s Volume 14, Issue 16, entitled, “Synergism of BCL-2 family inhibitors facilitates selective elimination of senescent cells.”
Accumulation of senescent cells in tissues with advancing age participates in the pathogenesis of several human age-associated diseases. Specific senescent secretome, the resistance of senescent cells to apoptotic stimuli, and lack of immune system response contribute to the accumulation of senescent cells and their adverse effects in tissues…
![Figure 1. Risk of mortality and morbidity associated with serum IGF-1 levels, stratified by age groups [5].](https://aging-us.net/wp-content/uploads/2022/08/Screen-Shot-2022-08-31-at-4.14.07-PM.png)
Figure 1. Risk of mortality and morbidity associated with serum IGF-1 levels, stratified by age groups [5].
Background: While iron is essential for normal brain functioning, elevated concentrations are commonly found in neurodegenerative diseases and are associated with impaired cognition and neurological deficits.
Dr. Steve Horvath and Dr. Brian Chen discuss the evolution of aging research and epigenetic clocks.