In the present study, researchers estimated the DNA methylation-based age (DNAmage) using four epigenetic clocks based on a small number of CpGs in French centenarians and semi-supercentenarians (CSSC, n=214) as well as nonagenarians’ and centenarians’ offspring (NCO, n=143) compared to individuals from the French general population (CG, n=149)…

The researchers have developed a deep learning aging clock using blood test data from the China Health and Retirement Longitudinal Study, which has a mean absolute error of 5.68 years. They used the aging clock to demonstrate the connection between the physical and psychological aspects of aging…

Background: Aging-related cognitive decline is an early symptom of Alzheimer’s disease and other dementias, and on its own can have substantial consequences on an individual’s ability to perform important everyday functions…