GV1001, which mimics the activity of human telomerase reverse transcriptase, protects neural cells from amyloid beta (Aβ) toxicity and other stressors through extra-telomeric function, as noted in the researchers prior in vitro studies….

The impact of the senescence related microenvironment on cancer prognosis and therapeutic response remains poorly understood. In this study, researchers investigated the prognostic significance of senescence related tumor microenvironment genes (PSTGs) and their potential implications for immunotherapy response…

Observational studies in preclinical models demonstrate age-related declines in circadian functions. The researchers hypothesized that age would be associated with declines in function of cell-autonomous circadian clocks in human tissue.