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Aging (Aging-US) Authors

Aging Volume 17, issue 3
Aging News

Senolytics Target Alzheimer’s-Linked Brain Enzymes Without Harming Healthy Ones

April 1, 2025April 1, 2025

A new research paper was published in Aging (Aging-US) on March 29, 2025, as the cover of Volume 17, Issue 3, titled “Differential senolytic inhibition of normal versus Aβ-associated cholinesterases: implications in aging and Alzheimer’s disease.”

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Aging Volume 17, issue 3
Aging Latest Issue

Differential senolytic inhibition of normal versus Aβ-associated cholinesterases: implications in aging and Alzheimer’s disease

March 31, 2025March 31, 2025

Cellular senescence is a hallmark of aging and the age-related condition, Alzheimer’s disease (AD). How senescence contributes to cholinergic and neuropathologic changes in AD remains uncertain. Furthermore, little is known about the relationship between senescence and cholinesterases (ChEs).

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Brain Aging and Alzheimer’s: Insights from Non-Human Primates
Aging News

Brain Aging and Alzheimer’s: Insights from Non-Human Primates

November 19, 2024November 19, 2024

A new review was published in Aging (listed by MEDLINE/PubMed as “Aging (Albany NY)” and “Aging-US” by Web of Science), on October 29, 2024, Volume 16, Issue 20, titled, ”Brain aging and Alzheimer’s disease, a perspective from non-human primates.“

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Aging
Aging News

The Memtrax Continuous Recognition Test for Advanced Cognitive Impairment Screening

July 13, 2023July 13, 2023

PRESS RELEASE: A new editorial paper was published in Aging’s Volume 15, Issue 12, entitled, “Advancing screening for cognitive impairment: the memtrax continuous recognition test.”

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Stress granules sequester Alzheimer’s disease-associated gene transcripts and regulate disease-related neuronal proteostasis
Aging News

Stress Granules Control Alzheimer’s Gene Transcripts and Neuronal Proteostasis

June 1, 2023June 1, 2023

PRESS RELEASE: A new research paper was published on the cover of Aging’s Volume 15, Issue 10, entitled, “Stress granules sequester Alzheimer’s disease-associated gene transcripts and regulate disease-related neuronal proteostasis.”

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Figure 2. Univariate associations of minor alleles of four SNPs from the MLXIPL gene with AD and CHD in two samples drawn from US cohorts (A) and UK biobank (B).
Aging News

External Factors Shape Genetic Predisposition to Lipids, Alzheimer’s and Heart Disease in MLXIPL Gene

May 24, 2023May 24, 2023

PRESS RELEASE: A new research paper was published in Aging’s Volume 15, Issue 9, entitled, “Exogenous exposures shape genetic predisposition to lipids, Alzheimer’s, and coronary heart disease in the MLXIPL gene locus.”

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Figure 5. Platelet depletion increases astrocytic coverage of fibrillary amyloid plaques.
Aging News

Aging | Immune-mediated Platelet Depletion Augments Alzheimer’s Disease in Mice

February 15, 2023February 15, 2023

PRESS RELEASE: A new research paper was published on the cover of Aging’s Volume 15, Issue 3, entitled, “Immune-mediated platelet depletion augments Alzheimer’s disease neuropathological hallmarks in APP-PS1 mice.”

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Figure 1. A schematic diagram of potential APOE-related mechanism of Alzheimer’s disease (AD).
Aging News

Aging | Associations of APOE ε2 and ε4 Alleles and Polygenic Profiles Comprising APOE-TOMM40-APOC1 Variants With Alzheimer’s Disease Biomarkers

January 3, 2023January 5, 2023

PRESS RELEASE: A new research paper was published on the cover of Aging’s Volume 14, Issue 24, entitled, “Associations of the APOE ε2 and ε4 alleles and polygenic profiles comprising APOE-TOMM40-APOC1 variants with Alzheimer’s disease biomarkers.”

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Dr. Ya-Jen Chiu
Aging News Spotlight

Behind the Study: Novel TRKB Agonists Activate TRKB and Downstream ERK and AKT Signaling

November 1, 2022November 3, 2022

Dr. Ya-Jen Chiu discusses a research paper she co-authored that was published by Aging (Aging-US) in Volume 14, Issue 18, entitled, “Novel TRKB agonists activate TRKB and downstream ERK and AKT signaling to protect Aβ-GFP SH-SY5Y cells against Aβ toxicity.”

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Aging
Aging News

Aging | Extracellular microRNA and cognitive function in a prospective cohort of older men: The Veterans Affairs Normative Aging Study

September 15, 2022September 16, 2022

PRESS RELEASE: A new research paper was published on the cover of Aging’s Volume 14, Issue 17, entitled, “Extracellular microRNA and cognitive function in a prospective cohort of older men: The Veterans Affairs Normative Aging Study.”

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