PRESS RELEASE – A new research paper was published in Aging (listed by MEDLINE/PubMed as “Aging (Albany NY)” and “Aging-US” by Web of Science), Volume 16, Issue 19 on September 26, 2024, entitled, “Use of the senolytics dasatinib and quercetin for prevention of pelvic organ prolapse in a mouse animal model.”
Aging (Aging-US) Authors
![2-Bromopalmitate Reduces Senescence in Human Cells: Role of Palmitoylation](https://aging-us.net/wp-content/uploads/2024/09/Screen-Shot-2024-09-09-at-11.24.12-AM-800x600.png)
PRESS RELEASE – A new research paper was published in Aging (listed by MEDLINE/PubMed as “Aging (Albany NY)” and “Aging-US” by Web of Science), Volume 16, Issue 16 on August 23, 2024, entitled, “2-Bromopalmitate treatment attenuates senescence phenotype in human adult cells – possible role of palmitoylation.”
![Lipid Accumulation Drives Cellular Senescence in Dopaminergic Neurons](https://aging-us.net/wp-content/uploads/2024/08/Screen-Shot-2024-08-13-at-11.17.49-AM-800x600.png)
PRESS RELEASE – A new research perspective was published in Aging (listed by MEDLINE/PubMed as “Aging (Albany NY)” and “Aging-US” by Web of Science), Volume 16, Issue 14 on July 19, 2024, entitled, “Lipid accumulation drives cellular senescence in dopaminergic neurons.”
![Figure 1. Morphological changes of human corneal endothelial cells after UV-A exposition.](https://aging-us.net/wp-content/uploads/2024/04/Screen-Shot-2024-04-30-at-1.45.59-PM-800x600.png)
PRESS RELEASE: A new research paper was published on the cover of Aging’s Volume 16, Issue 8, entitled, “Senescent characteristics of human corneal endothelial cells upon ultraviolet-A exposure.”
![Figure 8. PR55α level is much lower in human normal tissue specimens of older individuals compared to younger individuals and inversely correlates with p16 levels. Human normal tissue specimens derived from various organs/sites were analyzed for differences in PR55α and p16 expression by IHC.](https://aging-us.net/wp-content/uploads/2024/03/Screen-Shot-2024-03-19-at-10.27.34-AM-800x464.png)
PRESS RELEASE: On March 4, 2024, a new research paper was published in Aging’s Volume 16, Issue 5, entitled, “PR55α-controlled protein phosphatase 2A inhibits p16 expression and blocks cellular senescence induction by γ-irradiation.”
![Figure 6. Immunotherapy response prediction of senescence related TME risk model and STCGs expression in single cell level.](https://aging-us.net/wp-content/uploads/2024/01/Screen-Shot-2024-01-31-at-2.46.14-PM-800x600.png)
PRESS RELEASE: A new research paper was published on the cover of Aging’s Volume 16, Issue 2, entitled, “Prognostic significance of senescence-related tumor microenvironment genes in head and neck squamous cell carcinoma.”
![Figure 1. Identification of CaV blockers as a potential new class of senolytics.](https://aging-us.net/wp-content/uploads/2023/12/Screen-Shot-2023-12-20-at-2.23.07-PM-800x600.png)
PRESS RELEASE: A new research paper was published in Aging’s Volume 15, Issue 23, entitled, “Benidipine calcium channel blocker promotes the death of cigarette smoke-induced senescent cells and improves lung emphysema.”
![Figure 2. Comprehensive transcriptional analysis of senescent corneal and conjunctival epithelial cells.](https://aging-us.net/wp-content/uploads/2023/10/Screen-Shot-2023-10-02-at-3.05.51-PM-800x600.png)
PRESS RELEASE: A new priority research paper was published on the cover of Aging’s Volume 15, Issue 18, entitled, “Gene expression signatures of human senescent corneal and conjunctival epithelial cells.”
![Figure 1. Experimental design. To investigate senescence in osteoarthritic chondrocytes, primary human articular chondrocytes (HACs) were stimulated with etoposide for 24 h (blue) or with IL-1β for 8 days (red) with treatment renewal at days 3 and 6. Senescence features were assessed at days 1 and 8 in both conditions by qPCR, WB, and immunofluorescence.](https://aging-us.net/wp-content/uploads/2023/09/Screen-Shot-2023-09-20-at-2.14.02-PM-800x600.png)
A new research paper was published in Aging’s Volume 15, Issue 17, entitled, “Development of a DNA damage-induced senescence model in osteoarthritic chondrocytes.”
![Figure 4. The secretome of senescent human lung fibroblasts as mediator of murine lung fibrosis.](https://aging-us.net/wp-content/uploads/2023/07/Screen-Shot-2023-07-31-at-2.43.43-PM-800x600.png)
PRESS RELEASE: A new research paper was published on the cover of Aging’s Volume 15, Issue 14, entitled, “Human senescent fibroblasts trigger progressive lung fibrosis in mice.”