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Aging (Aging-US) Authors

Figure 1. The main method utilized in the work.
Aging News

AI Model for Age-Related Disease Target Discovery

October 4, 2023October 4, 2023

PRESS RELEASE: A new research paper was published in Aging’s Volume 15, Issue 18, entitled, “Biomedical generative pre-trained based transformer language model for age-related disease target discovery.”

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Figure 2. Comprehensive transcriptional analysis of senescent corneal and conjunctival epithelial cells.
Aging News

Genetic Profiles of Senescent Corneal and Conjunctival Epithelial Cells in Humans

October 2, 2023October 2, 2023

PRESS RELEASE: A new priority research paper was published on the cover of Aging’s Volume 15, Issue 18, entitled, “Gene expression signatures of human senescent corneal and conjunctival epithelial cells.”

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Aging Volume 15, Issue 18
Aging Latest Issue

Gene expression signatures of human senescent corneal and conjunctival epithelial cells

September 30, 2023September 30, 2023

The researchers examined cell morphology, senescence-associated β-galactosidase (SA-β-gal) activity, cell proliferation, and expression of senescence markers (p16 and p21). RNA sequencing analysis was conducted to compare gene expression profiles between senescent and non-senescent cells…

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High-throughput single-cell profiling of B cell responses following inactivated influenza vaccination in young and older adults
Aging Latest Issue

High-throughput single-cell profiling of B cell responses following inactivated influenza vaccination in young and older adults

September 30, 2023September 30, 2023
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Effect of cognitive reserve on the association between slow wave sleep and cognition in community-dwelling older adults
Aging Latest Issue

Effect of cognitive reserve on the association between slow wave sleep and cognition in community-dwelling older adults

September 30, 2023September 30, 2023
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Aging
Aging News

Opportunities to Improve Lung Cancer Care for Older Patients

September 27, 2023September 27, 2023

PRESS RELEASE: A new editorial paper was published in Aging’s Volume 15, Issue 17, entitled, “Promising trends in lung cancer care, but are we overlooking the majority?”

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Figure 4. Prediction model performance.
Aging News

Living Donor Liver Transplant Access is Optimal for High-risk Waitlisted Cirrhosis Patients

September 26, 2023September 26, 2023

PRESS RELEASE: A new research paper was published in Aging’s Volume 15, Issue 17, entitled, “Availability of living donor optimizes timing of liver transplant in high-risk waitlisted cirrhosis patients.”

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Figure 1. Experimental design. To investigate senescence in osteoarthritic chondrocytes, primary human articular chondrocytes (HACs) were stimulated with etoposide for 24 h (blue) or with IL-1β for 8 days (red) with treatment renewal at days 3 and 6. Senescence features were assessed at days 1 and 8 in both conditions by qPCR, WB, and immunofluorescence.
Aging News

DNA Damage-induced Senescence Model in Osteoarthritic Chondrocytes

September 20, 2023September 20, 2023

A new research paper was published in Aging’s Volume 15, Issue 17, entitled, “Development of a DNA damage-induced senescence model in osteoarthritic chondrocytes.”

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Figure 1. Basic principles of the 1st and next gen DNAme EN clocks.
Aging News

Development of a Noise Barometer for Measuring Epigenetic Pressure of Aging and Disease

September 18, 2023September 18, 2023

PRESS RELEASE: A new priority research paper was published on the cover of Aging’s Volume 15, Issue 17, entitled, “Fail-tests of DNA methylation clocks, and development of a noise barometer for measuring epigenetic pressure of aging and disease.”

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Aging Volume 15, Issue 17
Aging Latest Issue

Fail-tests of DNA methylation clocks, and development of a noise barometer for measuring epigenetic pressure of aging and disease

September 15, 2023September 15, 2023

This study shows that Elastic Net (EN) DNA methylation (DNAme) clocks have low accuracy of predictions for individuals of the same age and a low resolution between healthy and disease cohorts; caveats inherent in applying linear model to non-linear processes.

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