PRESS RELEASE: A new research paper was published in Aging’s Volume 15, Issue 18, entitled, “Biomedical generative pre-trained based transformer language model for age-related disease target discovery.”
Aging (Aging-US) Authors
PRESS RELEASE: A new priority research paper was published on the cover of Aging’s Volume 15, Issue 18, entitled, “Gene expression signatures of human senescent corneal and conjunctival epithelial cells.”
The researchers examined cell morphology, senescence-associated β-galactosidase (SA-β-gal) activity, cell proliferation, and expression of senescence markers (p16 and p21). RNA sequencing analysis was conducted to compare gene expression profiles between senescent and non-senescent cells…
PRESS RELEASE: A new editorial paper was published in Aging’s Volume 15, Issue 17, entitled, “Promising trends in lung cancer care, but are we overlooking the majority?”
PRESS RELEASE: A new research paper was published in Aging’s Volume 15, Issue 17, entitled, “Availability of living donor optimizes timing of liver transplant in high-risk waitlisted cirrhosis patients.”
A new research paper was published in Aging’s Volume 15, Issue 17, entitled, “Development of a DNA damage-induced senescence model in osteoarthritic chondrocytes.”
PRESS RELEASE: A new priority research paper was published on the cover of Aging’s Volume 15, Issue 17, entitled, “Fail-tests of DNA methylation clocks, and development of a noise barometer for measuring epigenetic pressure of aging and disease.”
This study shows that Elastic Net (EN) DNA methylation (DNAme) clocks have low accuracy of predictions for individuals of the same age and a low resolution between healthy and disease cohorts; caveats inherent in applying linear model to non-linear processes.