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Aging-US.net features press releases on the latest aging research, plus interviews and from the distinguished network of authors who continue to publish their research with Aging-US.

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Aging Journal

Figure 6. p16Ink4a-expressing cells do not proliferate or secrete SASP compared to other senescent cells.
Aging News

Aging | Clearance of p16Ink4a+ Cells: Limited Effects on B-Cell Mass and Proliferation in Mice

January 31, 2023January 31, 2023

PRESS RELEASE: A new research paper was published on the cover of Aging’s Volume 15, Issue 2, entitled, “Clearance of p16Ink4a-positive cells in a mouse transgenic model does not change β-cell mass and has limited effects on their proliferative capacity.”

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Figure 3. fbxc-58 mediates dietary restriction effects on mitigating muscle aging.
Aging News

Aging | FBXC-58 Mediates Dietary Restriction Effects on Healthy Aging in C. Elegans

January 25, 2023January 25, 2023

PRESS RELEASE: A new research paper was published in Aging’s Volume 15, Issue 1, entitled, “The innate immune signaling component FBXC-58 mediates dietary restriction effects on healthy aging in Caenorhabditis elegans.”

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Figure 2. Genetic deficiency of RORα increased lesion size and vascular leakage in a mouse model of laser-induced choroidal neovascularization (CNV).
Aging News

Aging | Genetic Deficiency and Pharmacological Modulation of RORα Regulate Laser-Induced Choroidal Neovascularization

January 18, 2023January 18, 2023

PRESS RELEASE: A new research paper was published in Aging’s Volume 15, Issue 1, entitled, “Genetic deficiency and pharmacological modulation of RORα regulate laser-induced choroidal neovascularization.”

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Figure 1 (Fragmented): t-SNE visualization of 14,588 old and young peripheral blood cells.
Aging News

Aging | Single-Cell Transcriptomics of Peripheral Blood in Aging Mouse

January 17, 2023January 17, 2023

PRESS RELEASE: A new research paper was published on the cover of Aging’s Volume 15, Issue 1, entitled, “Single-cell transcriptomics of peripheral blood in the aging mouse.”

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Volume 15, Issue 1
Aging Latest Issue

Single-cell transcriptomics of peripheral blood in the aging mouse

January 15, 2023January 15, 2023

Compositional and transcriptional changes in the hematopoietic system have been used as biomarkers of immunosenescence and aging. Here, researchers use single-cell RNA-sequencing to study the aging peripheral blood in mice and characterize the changes in cell-type composition and transcriptional profiles associated with age.

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The innate immune signaling component FBXC-58 mediates dietary restriction effects on healthy aging in Caenorhabditis elegans
Aging Latest Issue

The innate immune signaling component FBXC-58 mediates dietary restriction effects on healthy aging in Caenorhabditis elegans

January 15, 2023March 15, 2023
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Genetic deficiency and pharmacological modulation of RORα regulate laser-induced choroidal neovascularization
Aging Latest Issue

Genetic deficiency and pharmacological modulation of RORα regulate laser-induced choroidal neovascularization

January 15, 2023March 15, 2023
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Figure 6. Hypothesis: some circRNAs mobilize within the motor neuron to the NMJ/muscle during the progression of ALS.
Aging News

Aging | Transcriptomic Analysis of Human ALS Skeletal Muscle Reveals…

January 12, 2023January 12, 2023

PRESS RELEASE: On December 30, 2022, Aging published a new research paper entitled, “Transcriptomic analysis of human ALS skeletal muscle reveals a disease-specific pattern of dysregulated circRNAs.”

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Figure 3. Interaction between biological age and HIV status on the posterior cingulate theta response and the medial prefrontal cortex alpha response.
Aging News

Aging | Epigenetic Aging Associated With Aberrant Neural Oscillatory Dynamics Serving Visuospatial Processing in People With HIV

January 5, 2023January 5, 2023

PRESS RELEASE: A new research paper was published in Aging’s Volume 14, Issue 24, entitled, “Epigenetic aging is associated with aberrant neural oscillatory dynamics serving visuospatial processing in people with HIV.”

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Figure 1. A schematic diagram of potential APOE-related mechanism of Alzheimer’s disease (AD).
Aging News

Aging | Associations of APOE ε2 and ε4 Alleles and Polygenic Profiles Comprising APOE-TOMM40-APOC1 Variants With Alzheimer’s Disease Biomarkers

January 3, 2023January 5, 2023

PRESS RELEASE: A new research paper was published on the cover of Aging’s Volume 14, Issue 24, entitled, “Associations of the APOE ε2 and ε4 alleles and polygenic profiles comprising APOE-TOMM40-APOC1 variants with Alzheimer’s disease biomarkers.”

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