Capturing the genetic architecture of Alzheimer’s disease (AD) is challenging because of the complex interplay of genetic and non-genetic factors in its etiology. It has been suggested that AD biomarkers may improve the characterization of AD pathology and its genetic architecture…
Aging Journal
PRESS RELEASE: A new research paper was published in Aging’s Volume 14, Issue 23, entitled, “DNA methylation-based measures of biological aging and cognitive decline over 16-years: preliminary longitudinal findings in midlife.”
PRESS RELEASE: A new research paper was published in Aging’s Volume 14, Issue 23, entitled, “White matter hyperintensity load is associated with premature brain aging.”
PRESS RELEASE: A new research paper was published in Aging’s Volume 14, Issue 23, entitled, “DNA methylation GrimAge version 2.”
To gain deeper insights into age-related muscle loss, the researchers performed transcriptome profiling on lower limb muscle biopsies from 72 young, elderly, and frail human subjects using bulk RNA-seq (N = 72) and single-nuclei RNA-seq (N = 17)…
PRESS RELEASE: A new research paper was published on the cover of Aging’s Volume 14, Issue 23, entitled, “Single nuclei profiling identifies cell specific markers of skeletal muscle aging, frailty, and senescence.”