PRESS RELEASE: A new research paper was published in Aging’s Volume 15, Issue 2, entitled, “Body weight influences musculoskeletal adaptation to long-term voluntary wheel running during aging in female mice.”
Aging (Aging-US) Authors
PRESS RELEASE: Dr. Blagosklonny published a new research perspective in Aging’s Volume 15, Issue 2, entitled, “Are menopause, aging and prostate cancer diseases?”
Type 2 diabetes is partly characterized by decreased β-cell mass and function which have been linked to cellular senescence. Despite a low basal proliferative rate of adult β-cells, they can respond to growth stimuli, but this proliferative capacity decreases with age and correlates with increased expression of senescence effector, p16Ink4a.
PRESS RELEASE: A new research paper was published on the cover of Aging’s Volume 15, Issue 2, entitled, “Clearance of p16Ink4a-positive cells in a mouse transgenic model does not change β-cell mass and has limited effects on their proliferative capacity.”
PRESS RELEASE: A new research paper was published in Aging’s Volume 15, Issue 1, entitled, “The innate immune signaling component FBXC-58 mediates dietary restriction effects on healthy aging in Caenorhabditis elegans.”
PRESS RELEASE: A new research paper was published in Aging’s Volume 15, Issue 1, entitled, “Genetic deficiency and pharmacological modulation of RORα regulate laser-induced choroidal neovascularization.”
PRESS RELEASE: A new research paper was published on the cover of Aging’s Volume 15, Issue 1, entitled, “Single-cell transcriptomics of peripheral blood in the aging mouse.”
Compositional and transcriptional changes in the hematopoietic system have been used as biomarkers of immunosenescence and aging. Here, researchers use single-cell RNA-sequencing to study the aging peripheral blood in mice and characterize the changes in cell-type composition and transcriptional profiles associated with age.